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p53 Mediated Bone Marrow Mesenchymal Stem Cell Expansion Supports Acute Myeloid Leukemia Development

Yao J, Takenaga K, Koshikawa N, Kida Y, Lin J, Watanabe T, Maru Y, Hippo Y, Yamamoto S, Zhu Y, et al

This research aims to provide theoretical references for developing novel therapeutic strategies

750mg/day) and flexible dosing was used to achieve a clinical response and/or a target serum valproate level of 80-125 mcg/ml with a maximum allowable dose set at 35mg/kg

In contrast, all DP-treated groups displayed a significant increase in vascular formation compared to the HG (30 mM) group, also showing a dose-dependent effect