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[,] Although one in three PBC patients who are treated with UDCA have no response to therapy, UDCA is still considered the first therapeutic choice for PBC

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Acetaminophen inhibits the synthesis of prostaglandin (PG) E2, PGF2, and thromboxane B2 by lipopolysaccharide (LPS)-stimulated microglia, yet has no effect on the levels of pro-inflammatory mediators such as tumor necrosis factor (TNF)- and NO [19,20]

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