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Associations among glutathione S-transferase T1, M1, and P1 polymorphisms and the risk of oral leukoplakia

Sheridan et al., 2016)

Journal of Pharmaceutical Science and Technology

Upregulation in phenylalanine (increased PAL), tyrosine (increased TYR, HPPD), arginine/proline (increased ARG, P5CR), and glycine/serine/threonine (increased AMT, TA) metabolism serves multiple protective functions: (1) Antioxidant Production: PAL activation promotes phenolic antioxidant synthesis