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When a ligand binds to the extracellular receptor, this initiates a signal transduction cascade that induces a conformational change, promoting the activation of the heterotrimeric GTP-binding protein (G-protein) (79)

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AOD-9604 is for research use only

If other expression hosts are to be screened, there are universal cloning systems commercially available (e.g., Gateway cloning system at Unit 5.17) that allow the rapid transfer of the gene of interest into multivector systems including yeast, baculovirus, and mammalian cells