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The SLC22 transporter family: a paradigm for the impact of drug transporters on metabolic pathways, signaling, and disease

Its proposed mechanisms include the enhancement of lipid metabolism, improvement of insulin sensitivity, stabilization of hepatocyte function, and reduction of inflammation, fibrosis, and tumorigenesis

Parenteral delivery may also have implications for the safety of long-term treatment with acetyl-l-carnitine as described in the Safety section below

The previously published model of fatty-acid oxidation in rat [16] is available through the JWS online database ( All mouse and human model files are in the supplemental material (Additional file 5: Model S5, Additional file 7: Figure S7, Additional file 8: Model S8, Additional file 9: Model S9, and Additional file 10: Model S10) and the physiologically relevant Models S5 and S9 were submitted to the JWS online database (jjj.biochem.sun.ac.za) where they will soon be searchable under the name vaneunen

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling