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It remains not clear why this surface residue Cys396, located far away from the monomer interaction could lead to monomerization

doi: 10.1016/j.redox.2022.102438 158 NitureSLinMQiQMooreJTLevineKEFernandoRAet al

Apiradee U, Shina Q, Natdanai M, et al

Cellular cisplatin accumulation is mainly determined by copper transporter-1, responsible for cisplatin uptake 6,7 and ABCB1 , encoding multidrug-resistant protein 1 (MDR1) involved in increasing platinum-drug export 8,9