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In vivo, enhancing PEP production through overexpression of PCK1, an enzyme that produced PEP from oxaloacetate, is sufficient to enhance CD4 and CD8 T cell function in murine tumor models, suggesting that glycolytic regulation of signaling is a mechanism by which glucose-replete tumors evade immune responses

Benzyl alcohol disrupts microbial membrane integrity and interferes with microbial metabolic processes at concentrations sufficient to prevent colony growth but below cytotoxic thresholds for mammalian cells in most research applications

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and SLC22A12 , which encodes URAT1 ( Figure 1 - 4B )

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