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Matis, M

J Allergy Clin Immunol 122(3):507511 e6 Thompson CA, Eslick SR, Berthon BS, Wood LG (2021) Asthma medication use in obese and healthy weight asthma: systematic review/meta-analysis

Several additional differences exist between schistosome TGR and mammalian TGR, TrxR1, TrxR2, or GR

The mechanism is scientifically sound and consistently supported by animal data, but human efficacy and safety have not been established through clinical trials

The large decreases in calculous events seen when placebo or ineffective therapy is given underscore the positive treatment bias that occurs when historical controls are used and they demonstrate the need for proper experimental design [2]