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Washington, D.C.: NewTrends Publishing

M., Shaye, D., & Ferrara, K

Recognizing these triggers can help individuals make lifestyle changes to prevent future occurrences

LDHA expression is directly regulated by transcription factors such as c-Myc and hypoxia-inducible factor 1 (HIF-1), with the latter further increasing lactate production by blocking pyruvate entry into mitochondria [65, 66]