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The earliest diagnosis of vitiligo is essential for the management of potential psychological and emotional symptoms that may result from the skin condition

2017;7(1):12860.doi:10.1038/s41598-017-13034-7 Mendes da Silva D, Gross LA, NetoEPG, Lessey BA, Savaris RF

Although analyzing DNA methylation in blood as a surrogate for brain has its limitations with regard to underrepresentation of the alterations that take place in the disease-affected tissue, it has a potential use in the identification of biomarkers that could help diagnosis and disease monitoring

The recovery of all plasma samples ranged between 96.23% and 108.77%, whereas that of the brain tissue sample was between 96.57% and 106.51%

& Komiyama, A