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Lipid peroxides can promote a cascade of oxidative damage in tissues, contributing to the tissue damage in the intestine that is characteristic of celiac disease, and to the increased risk of cancer in celiac patients (Stojiljkovic 2007

doi: 10.1038/modpathol.2016.160 20 BosseTter HaarNTSeeberLMDiestPHesFJVasenHFAet al

Using this DT, a potential scenario distinguishing regeneration of a characteristic cell death pattern after acute hepatotoxic insult and repeated hepatotoxic exposure leading to formation of septal fibrotic walls is proposed based on the spatial pattern of CYP2E1 (key metabolic enzyme) expressing cells

These effects included reduction of vWF multimer size, removal of ULVWF strings from the endothelial surface, and marked shortening of the time to reestablish normal blood flow in the microvasculature of ADAMTS13-deficient mice challenged to secrete vWF