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115,116 In addition, under glucose deprivation, AMPK directly phosphorylates WDR24, subsequently disrupting the integrity of the GATOR2 complex and leading to mTORC1 inactivation

doi: 10.1016/j.arr.2024.102244, 161

The combination according to the invention, in any form, may be suitable for administration to human subjects, the preferred administration route being oral administration