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Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg/kg intravenous acetaminophen in very-preterm infants

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Mitochondrial TCA cycle activity, fatty acid -oxidation, and amino acid metabolism contribute to ROS generation that, in concert with iron, amplify LP and drive ferroptotic signaling ( Figure 1 Morphologically, ferroptosis diverges from classical apoptosis and necrosis