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Cleansing creates a clean canvas for subsequent products

This mechanistic distinction suggests the two agents could be synergistic rather than redundant, though that hypothesis has not been tested in a published clinical trial as of January 2025

doi: 10.1186/1471-2180-14-137

Posttranslational modifications of ROS-mediated kinase activity most probably contribute to the diversity and intensity of gene expression following microbial activation of innate immunity (Kolls, 2006)