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This was attributed to spermidines ability to activate mitophagy and autophagy, helping maintain mitochondrial quality and preventing the accumulation of damaged mitochondria in heart tissue (Reference Eisenberg, Abdellatif and Schroeder80)

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To enhance the chemical interactions between the inert recycled SMC and the fresh UPR, and as consequence their mechanical properties, two different transesterification catalysts, aluminum (III) sec-butoxide and titanium (IV) butoxide at 1.0 wt%, were utilized

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Interestingly, gating of SKOR is tightly regulated by its substrate concentration at either side of the membrane (Figure 1)