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4I), although ACSL4 showed no significant change

Shaw, 2022)

Structure-Based Design and Identification of FT-2102 (Olutasidenib), a Potent Mutant-Selective IDH1 Inhibitor

PMID: 29263482

These redox-regulatory effects are particularly relevant in PCOS, where a disrupted follicular microenvironment and heightened OS negatively impact fertility outcomes (146), and are discussed in greater mechanistic detail in Section 4.3