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This section delineates the core cellular stress pathwaysincluding endoplasmic reticulum stress, oxidative stress, mitophagy dysfunction, and epigenetic reprogrammingthat drive pulmonary injury in diabetes at the molecular level (Figure 3)

(2019b) found that AIM2 inflammasome, ASC, cleaved caspase-1, and IL-1 were markedly elevated in the spinal cord tissue of ischemia/reperfusion mouse models and positively correlated with sustained dysfunction

Administration of SOD SOD supplementation may be a useful preventive measure to lower the risk of excessive formation of free radicals

Impact of endolysosomal dysfunction upon exosomes in neurodegenerative diseases

Free Radic Biol Med 52(5):92836 Ding YW, Zhao GJ, Li XL, Hong GL, Li MF, Qiu QM et al (2016) SIRT1 exerts protective effects against paraquat-inducedinjury in mouse type II alveolar epithelial cellsby deacetylating NRF2 in vitro