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In recent years there has been a significant upsurge in the volume of research initiated to better understand the underlying postbiotic mechanisms

Endometrial tissue repair The endometrium is the only human tissue that undergoes periodic breakdown and regeneration, necessitating a transition of tissue cells between mesenchymal and epithelial phenotypes, a process known as mesenchymal-epithelial transition and epithelial-mesenchymal transition [470, 471]

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Theoretical Long-Term Risks TB500 enhances angiogenesis and cellular proliferation, which has raised concerns primarily in preclinical models about: Accelerating growth of dormant tumors Disrupting immune surveillance Overstimulating wound healing in healthy tissues There is no conclusive evidence that TB500 causes cancer, but its role in cell migration warrants caution, especially at high doses or long-term use without breaks

In our experience, if you use proper sterile procedures and refrigerated storage, you can continue sampling from the same reconstituted vial for 3+ months