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Description

Section 4 summarizes delivery systems and formulation strategies to address bioavailability and mucosal retention (e.g., mouthrinses, gels/orabases, nanoparticles, mucoadhesive films, and photosensitizers for PDT)

Valacchi G, Magnani N, Woodby B, Ferreira SM, Evelson P

This phenomenon has been corroborated by autopsy findings in PD patients, which reveal a significant presence of activated microglia in the substantia nigra and basal ganglia regions of their brains, whereas microglia in the brain tissue of healthy individuals remain in a quiescent state ( , IFN- ) were observed, alongside a decrease in anti-inflammatory factor levels