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Description

Metabolic requirements of the nephron

no defect in O 2 .- metabolism)

In some instances a once off boost is all that is required

doi: 10.1002/mds.26102 202

Chen found in human melanoma cells that silencing iPLA2 would enhance the sensitivity to p53-mediated ferroptosis without significant effects on cells that usually express iPLA2, suggesting that iPLA2 can inhibit p53-mediated ferroptosis, and p53-driven ferroptosis is independent of GPX4 [41]