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doi: 10.2147/cmr.s5598 169 ZhangLWangH

Another mitokine, FGF21, alleviates brain cells apoptosis and improves hippocampal synaptic plasticity as well as dendritic spine density in obese-insulin resistant rats, thus providing neuroprotection and preventing cognitive deterioration [10]

This may potentially be because the cell death occurring in BT12 cells in response to cisplatin is ROS-dependent whereas this may not totally be the case in BT16 cells, due to the demonstrated higher expression levels of cytoprotective components of the antioxidant system, GSH and Nrf2

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This means even abdominal injections can support elbow healing, though local injections likely deliver faster and more pronounced local effects