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Cell suspensions were lysed by freeze-thawing, and PV VLPs were purified from clarified supernatants by concentration through a 30% sucrose cushion followed by a 1545% sucrose gradient in 1 Dulbeccos phosphate-buffered saline (DPBS, Gibco), 20 mM EDTA, pH 7.0 (DPBS-EDTA) 15

Calcium is a mineral essential for healthy bones and is also important for muscle contraction,

Some have suggested that the aforementioned drug V-9302 targets SLC38A2 and SLC7A5 instead of SLC1A5 [34, 87] (Fig

Furthermore, in vivo and in vitro data indicated that PPAR activation restored Pink1/Parkin-dependent mitophagy, improved mitochondrial function, inhibited chondrocyte ferroptosis, and delayed the progression of OA