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Clinical progress of metformin combined with standard anticancer drugs In recent years, under single treatment regimens [chemotherapy, immune checkpoint inhibitors (ICIs) and targeted therapies] patients have exhibited relapses due to the development of acquired drug resistance (101103)

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Its enhanced chemical stability, particularly for oral research applications, is its defining characteristic and key advantage over the traditional acetate salt

10.1016/0009-8981(94)05991-z 211 PortalB

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