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Growth factors are not simply involved in driving growth of the tumour, they can also impact the tumour microenvironment (Zhang et al., 2010), and cancer-cell de-differentiation (Witsch et al., 2010)

LDs store PUFAs, which are highly susceptible to oxidation

A good prescriber matches the tool to the patient, not the other way around

No therapy is risk-free, and growth hormone signaling is powerful, which is the entire reason for medical supervision and lab monitoring

for instance, a recent phase II trial demonstrated that combining an ALOX15 inhibitor with low-dose corticosteroids significantly reduced the annualized exacerbation rate compared to corticosteroid monotherapy (161)