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10.1155/2013/967029 J

A randomised controlled trial to test the analgesic efficacy of topical morphine on minor superficial and partial thickness burns in accident and emergency departments

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It appears to reset pathological gene expression, with observed effects on restoring function in dysfunctional systems

This distinction in transcriptional regulation, and the absence of a change to MT1 and MT2, suggests that decreased MT3 levels may not necessarily be a direct regulatory result of decreased copper levels but reflect parallel disease processes or broader copper dysregulation previously reported in the human ALS and MS spinal cord 15,16