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Injection site reactions to subcutaneous biologics: mechanisms and management. Journal of Clinical Immunology , 40(5), 745755

This is why ex vivo findings need to be confirmed in human trials which subsequent studies like the 2016 GHK peptide clinical trial and the 2021 copper tripeptide serum trial have done

Pre-clinical and cosmetic-research data describe increased collagen and elastin synthesis, fibroblast proliferation, improved barrier-protein expression, and reduced markers of oxidative stress following GHK-Cu exposure

When pentadecapeptide BPC 157 was given immediately after paracetamol, BPC 157 rats started to rear on hind legs and shake shortly after paracetamol application while after 10 minutes, they became sleepy, with a tottering walk, after 35 min they regained normal behavior, drank (but not excessively) and then ate and showed no behavioral abnormalities until their sacrifice ( Table 5 )

Youre not compounding a pharmaceutical