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Description

NCT04892136 (hair growth, Phase I/II, terminated 2023) clinicaltrials.gov

In a study of Hairpoor (HRHp) heterozygous mice (an animal model of MUHH), HR overexpression in epithelial cells and keratinocytes was found to block the Wnt/-catenin signalling pathway by upregulating DKK1 expression during the growth phase, promoting the degenerative progression of hair follicles

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