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Patients with even mid-range to high-range levels of vitamin B12 often still have a high MCV and high homocysteine (discussed below) and can benefit from vitamin B12 levels

Product Details: Vitamin B12: 5,000 mcg per oz Folic Acid: 3.22 mg per oz Supports normal energy and protein metabolism Supports healthy red blood cell formation Easy-to-administer liquid Size & Usage: 32 oz bottle - Approximately one-month supply per horse at the label rate Feed according to label directions based on weight and workload For equine use only View Full Product Label (PDF) A convenient daily B-vitamin supplement to help maintain normal energy metabolism and red blood cell formation in horses

[DOI] [PubMed] [Google Scholar] 93.Sikiric P., Seiwerth S., Grabarevic Z., Rucman R., Petek M., Jagic V., Turkovic B., Rotkvic I., Mise S., Zoricic I., et al

The rule is a heuristic, not a law, which is why outliers like cyclosporin (1,202 daltons but orally absorbed due to cyclic backbone and N-methylation removing H-bond donors) exist