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Among them, -3 PUFAs (EPA and DHA) and polyphenols (curcumin) are regarded as key nutrients with potent anti-inflammatory effects, and also the main effect components in the recommended dietary pattern, MD

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FIGURE 1 In the pathological process of AKI, apoptosis is mainly regulated in a coordinated manner through the mitochondrial pathway (endogenous apoptotic pathway), the death receptor pathway (exogenous apoptotic pathway), and the endoplasmic reticulum stress (ERS) pathway (Wang et al., 2022b