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Moreover, an antibodydrug conjugate combining the anti-CD26 monoclonal antibody YS110 with triptolide (Y-TR1) selectively targets CD26-positive cancer cells (malignant mesothelioma and leukemia), effectively inhibiting RNA polymerase II activity [1027]

Eckard C, Cole R, Lockwood J, Torres DM, Williams CD, Shaw JC, et al

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PMID: 9065401

The treatment restored the estrous cycle, improved ovarian index and serum hormone levels, and increased numbers of sinus follicles and CL in the mice