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2021;131:e139434

(B) QRT-PCR analysis of MAT2A mRNA in U251 and U87 cells transfected with MAT2A siRNA

Abnormalities in cholinergic receptors, particularly 7nAChRs, have been linked to neurodevelopmental disorders such as ASD [44]

However, several antioxidant defense systems (e.g., the SLC7A11-GSH-GPX4 system, Nrf2 signaling, and FSP1-CoQ10 system) can counteract cellular oxidative stress, thus blocking ferroptosis 31