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Description

Advances in structural biology and predictive modelling of flavoprotein-cofactor interactions promise to refine genetic diagnostics and pave the way for genotype-guided, riboflavin-based precision therapies

[PMC free article: PMC4532752] [PubMed: 26268692] 624

This intermediate is then oxidized by 4-hydroxythreonine-4-phosphate dehydrogenase (PdxA) and finally condensed with DXP, synthesized by DXP synthase (Dxs), via pyridoxine 5-phosphate synthase (PdxJ), yielding PNP