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Its atherogenic effects include abnormalities in cholesterol and bile acid metabolism, which cause inflammation and foam cell production

However, chronic or excessive inflammation shifts the balance toward tissue destruction

Michaeloudes C, Sukkar MB, Khorasani NM, Bhavsar PK, Chung KF (2011b) TGF- regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells

[DOI] [PMC free article] [PubMed] [Google Scholar] 140.Perroud N., Salzmann A., Prada P., Nicastro R., Hoeppli M.E., Furrer S., Ardu S., Krejci I., Karege F., Malafosse A

Molecular Docking investigation of anti-inflammatory herbal compounds as potential LOX-5 and COX-2 inhibitors