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It was noted that although nebulized NAC did not show superior results than normal saline in reducing density of mucus plugs in mechanically ventilated patients, mean secretion density was significantly lower in the NAC group (P=0.006) and NAC increased O 2 saturation significantly (P=0.014)

Statistical analyses were carried out using GraphPad Prism v9 (Boston, MA, USA)

Starting at 10 weeks of age, KDS12025 was administered via ad libitum drinking water at doses of 1 mg/kg/day and 10 mg/kg/day

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