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63 Prolonged skeletal muscle inactivity promotes mitochondrial dysfunction, resulting in increase in mitochondrial ROS production and leading to protracted oxidative stress and disturbed redox signaling, 64 which can exacerbate IR through multiple pathways such as JNK and NF-B pathways (Fig

SQSTM1 then recognizes the ubiquitinated PEX5 complex and triggers pexophagy (Zhang et al., 2015)

Nature 1972

Due to its involvement in one-carbon metabolism, there is considerable interest in treating cancer by inhibiting Ser biosynthesis (Amelio, Cutruzzola, Antonov, Agostini, & Melino, 2014)

The invasive nature of keloid and notable migratory activity of fibroblasts are a hallmark, which distinguishes keloids from other common scars