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An endoperoxide reactivity-based FRET probe for ratiometric fluorescence imaging of labile iron pools in living cells

In recent years, accumulating evidence suggests that oxidative stress, mitochondrial dysfunction, and disturbances in iron homeostasis serve as upstream triggers driving these pathological cascades (Luo et al., 2019

methylmalonyl CoA mutase converts methylmalonyl CoA to succinyl CoA, with 5-deoxy adenosyl cobalamin required as a cofactor

Azithromycin alleviates the severity of rheumatoid arthritis by targeting the unfolded protein response component of glucose-regulated protein 78 (GRP78)

However, a cavity on the capsid surface at an inter-protomer interface, where we previously reported extra electron density 7 , has recently been identified as potentially druggable, with micro-molar binding for a benzene-sulfonamide derivative 8