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While cART partially mitigates HIV-induced neuroinflammation and metabolite changes (67, 100), neuronal dysfunction (evidenced by reduced N-acetylaspartate [NAA]) and neuroinflammation (indicated by increased mI and choline [Cho]) persist in chronically infected individuals, often accompanied by axonal damage (68, 100)

23 Yet, recent research has confirmed the presence of Ti in the tissues surrounding mandibular implants

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Depletion of SIRT6 inactivates the Keap1-NRF2 pathway and downregulates GPX4 expression, and enhances the sensitivity of gastric cancer cells to sorafenib-induced ferroptosis (Hao et al., 2017)