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11, June 2007, pp

Low levels of ROS act as second messengers for activating inflammatory intracellular signaling, such as NF-B and MAP kinase pathways (30)

Significantly more potent and better tolerated than arsenic trioxide, Darinaparsin showed encouraging responses in T-cell lymphoma (Hosein et al., 2012) and AML (Nielsen et al., 2013) patients