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Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages

Vitiligo occurs when melanocytes are destroyed or stop working, driven mainly by an autoimmune process, with genetic and environmental contributors

As mitochondrial ROS appears to be the main source of oxidative stress in COPD, mentioned mitochondria-targeted antioxidants might be a more promising approach because they are able to cross the mitochondria lipid bilayer and reduce ROS at its source