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Notably, the partially unfolded domain functions as a damage-associated molecular pattern (DAMP) molecule, driving the release of pro-inflammatory cytokines including TNF- and IL-8 from fibroblasts and activating the TLR4/NF-B pathway [156,157,158]

Glutathione also helps support the structural integrity of joints and connective tissues

Firstly, the sample size was relatively small, which may constrain the generalizability of the findings

doi: 10.3389/fpls.2021.798230 22 EricksonJ.WeckwerthP.RomeisT.LeeJ

[DOI] [PubMed] [Google Scholar] 223.Nicolay J.P., Melchers S., Albrecht J.D., Assaf C., Dippel E., Stadler R., Wehkamp U., Wobser M., Zhao J., Burghaus I., et al