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The number of patients completing their follow-up measurements between November and April, which is the period of low sun exposure in the northern latitudes [22], was indeed markedly higher in the Optimum 2.0 group compared to the Optimum 1.0 group, especially at 3 years of follow-up (77% vs 50%)

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British Journal of Haematology 2010;148:195204

While there is ample evidence that B12, as an essential vitamin, has numerous health benefits, there is no evidence that B12 shots have greater benefit than a B12 supplement in pill form

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