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Description

J Neurochem

Beyond the raw energy deficit, chronic illness profoundly impacts the delicate balance of neurotransmitters in the brain

Under inflammatory conditions, astrocytes undergo alterations in mitochondrial dynamic and activate autophagy to maintain mitochondrial function

This correlates well with the suggestion that carnitine is involved in the inflammatory response and that the expression of OCTN2 in epithelia can be modulated by inflammatory cytokines such as INF- and TNF- (Pochini et al., 2019)