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Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models

2+ , lactate dehydrogenase (LDH), MDA, and lipid ROS, inhibited neuronal ferroptosis and lipid peroxidation, thereby ameliorating oxygen-glucose deprivation and reoxygenation (OGD/R)-induced neuronal injury

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Imai H, Hirao F, Sakamoto T, Sekine K, Mizukura Y, Saito M et al (2003) Early embryonic lethality caused by targeted disruption of the mouse PHGPx gene