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Gpx4 expression was decreased in Mac-CF AM cells at Day 3 and 5 post-inoculation ( Supplementary Figure 3E )

NOTE: All

A significant decrease of these marker proteins was observed in FOXO4-DRI treated group compared with the control group (Figure 2D)

Fluorescence microscopy studies have documented rapid cellular accumulation, with detectable intracellular concentrations within 30 minutes of external application at physiological concentrations