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however, it posits a regulatory mechanism where TIMPs modulate the activity of MMPs, thereby balancing extracellular matrix degradation and formation

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by Mika Baumeister ( Consistency is key

Of note, our patient did have a background of previous scattered atrophic cicatricial alopecic plaques involving the scalp in areas of discoid lupus involvement (Figure 2)

Microglia are activated by the increased production of pro-inflammatory and anti-inflammatory cytokines, chemokines, and other inflammatory molecules, and increased glutamate release, all of which remain in microglia (Hoeijmakers et al., 2016)