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They contribute significantly to various aspects of brain function, including brain development, learning and memory processes, and the maintenance of CNS homeostasis

PMID: 254 BellonoNWBayrerJRLeitchDBCastroJZhangCODonnellTAet al

Once the AMPK signalling pathway is activated, it regulates key enzymes in several metabolic pathways, including lipid and glucose metabolism, mitochondrial dynamics, autophagy, and protein synthesis through phosphorylation, thereby helping to restore mitochondrial energy homeostasis [96, 97], which, when disrupted, damages mitochondria