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Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells

To avoid collateral effects, more specific modulators of amino acids metabolism can be developed, through the use of monoclonal antibodies, mimetic peptides that activate receptors, proteolysis-targeting chimera degraders, and/or antisense nucleotides targeting genes (receptors, transporters, or enzymes) [252,253,254,255]