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Nevertheless, emerging evidence underscores the pivotal role of copper homeostasis in both vascular disorders and SCM pathogenesis, highlighting its potential as a critical therapeutic target in mitigating systemic inflammation and cardiac dysfunction (Figure 3)

Chemosphere 57:10071015 Oliveira EJ, Watson DG (2000) Liquid chromatographymass spectrometry in the study of the metabolism of drugs and other xenobiotics

This complex cleaves pro-IL-1 via caspase-1 to generate active IL-1 (a key inflammatory mediator), concurrently inducing gasdermin D-mediated pyroptosis

Further increasing cysteine levels from 0.1 to 1 mM, however, resulted in an additional increase in CDO expression of only 40%

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