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However, in evolutionary context it makes sense, as Met-derived GSLs are a later invention in plant evolution (both in comparison to other types of GSL and other types of secondary metabolites), and during evolution plants made use of already existing transporters from primary metabolism

The role of Glycoside Hydrolases in S

However, the accuracy of this hypothesis has not yet been determined (Peterson and Binder, 2019)

Early trials reported it to be generally well tolerated at low doses, but these studies were small and of short duration