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In a properly functioning liver, insulin binding increases glucose uptake and signals the cells to stop glucose production

however, this effect was increased with the addition of auranofin (Fig

Unfortunately, studies on this topic have mainly focused on normalising serum B12 concentrations with oral supplementation and should be interpreted with caution since the specific goal of treatment in symptomatic B12 deficiency is alleviating symptoms, and NOT to normalize B12 concentrations in the blood